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Additionally, upregulation of NO has also been implicated in the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease [78–80]

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5.2 PROGRESSIVE STAGES OF A B12 DEFICIENCY 5.3 SYMPTOMS OF VITAMIN B12 DEFICIENCY The following may occur: Anemia with megaloblastosis (remember, this does not always occur, nor does it always occur early on)